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. 1980 Apr;8(4):484-93.

Cell-cycle properties and proliferation kinetics of late erythroid progenitors in murine bone marrow

F C Monette, R B Kent, E J Weiner, R F Jarris Jr, P L Ouellette, J A Thorson, R D Zelick
  • PMID: 7461052

Cell-cycle properties and proliferation kinetics of late erythroid progenitors in murine bone marrow

F C Monette et al. Exp Hematol. 1980 Apr.

Abstract

The cell-cycle properties of marrow CFUE were assessed in normal regenerating cell preparations. In addition, the erythropoietin sensitivity of CFUE was correlated to the cell-cycle distribution of these cells. The results suggest a coupling of erythropoietin sensitivity to the S-phase of the CFUE cell cycle in so far as CFUE in G2/M/G1 were 2 to 10 times less sensitive to the hormone. It is concluded that the CFUE cell cycle per se is not a focus for erythropoietic regulation.

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