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Case Reports
. 1981 Feb;40(1):92-5.
doi: 10.1136/ard.40.1.92.

Hepatocellular disease in the giant-cell arteritis/polymyalgia rheumatica syndrome

A S Leong, M H Alp
Case Reports

Hepatocellular disease in the giant-cell arteritis/polymyalgia rheumatica syndrome

A S Leong et al. Ann Rheum Dis. 1981 Feb.

Abstract

An elderly man developed temporal arteritis and polymyalgia rheumatica with coexisting biochemical abnormalities of liver function. Biopsy revealed hepatic changes which have not been previously reported. There was hepatocellular necrosis and inflammation together with a prominent hyperplasia of perisinusoidal lipocytes of Ito. Temporal artery biopsy confirmed the presence of granulomatous panarteritis. Corticosteroid therapy produced rapid resolution of symptoms and reversion of liver function tests to normal.

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