Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1995 Aug;32(8):600-4.
doi: 10.1136/jmg.32.8.600.

Neuropsychological characteristics of Huntington's disease carriers: a double blind study

N K Rosenberg  1 , S A Sørensen, A L Christensen
Affiliations
Comparative Study

Neuropsychological characteristics of Huntington's disease carriers: a double blind study

N K Rosenberg et al. J Med Genet. 1995 Aug.

Abstract

A cohort of 33 people at risk for Huntington's disease (HD), applying for genetic testing, were tested with a battery of neuropsychological tests covering attentional, visuospatial, learning, memory, and planning functions. A psychiatric rating scale, SCL-90R, was also applied, mainly as a control, since cognitive dysfunction could be ascribed to functional disorders as well as neurodegenerative processes. Self-rating did not indicate any psychiatric symptoms in carriers or non-carriers. However, significantly inferior cognitive functioning in the gene carriers was disclosed by the neuropsychological tests. Primarily, attentional, learning, and planning functions were affected. It is concluded that premorbid cognitive decline occurs in HD.

PubMed Disclaimer

References

    1. Psychopharmacol Bull. 1973 Jan;9(1):13-28 - PubMed
    1. Psychol Med. 1993;Suppl 23:1-46 - PubMed
    1. J Clin Neuropsychol. 1982 Jul;4(2):173-83 - PubMed
    1. J Nerv Ment Dis. 1983 Aug;171(8):492-6 - PubMed
    1. Psychol Med. 1983 Aug;13(3):537-42 - PubMed

Publication types

MeSH terms