A technique for the simultaneous staining of both nucleolar organizer regions and kinetochores of human chromosomes with silver
- PMID: 74868
- DOI: 10.3109/10520297709116804
A technique for the simultaneous staining of both nucleolar organizer regions and kinetochores of human chromosomes with silver
Abstract
Pretreatment of human metaphase chromosomes with NaOH at a pH of 8.5, followed by staining with silver nitrate, differentially stains both the nucleolar organizer regions on the 10 acrocentric chromosomes as well as the kinetochore centers on all 46 chromosomes.