The directed evolution of radiation resistance in E. coli
- PMID: 7488146
- DOI: 10.1006/bbrc.1995.2657
The directed evolution of radiation resistance in E. coli
Abstract
E. coli AB1157 (a wild-type, K-12 strain having no known defects in DNA repair capability) was irradiated daily with a very large X-ray dose to develop a series of strains unusually resistant to both X rays and ultraviolet (UV) photons. An understanding of how wild-type strains mutate and become more resistant should lead to a better understanding of DNA repair processes and their effects on radiation sensitivity.
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