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Comparative Study
. 1995 Nov 13;216(2):549-53.
doi: 10.1006/bbrc.1995.2657.

The directed evolution of radiation resistance in E. coli

Affiliations
Comparative Study

The directed evolution of radiation resistance in E. coli

D Ewing. Biochem Biophys Res Commun. .

Abstract

E. coli AB1157 (a wild-type, K-12 strain having no known defects in DNA repair capability) was irradiated daily with a very large X-ray dose to develop a series of strains unusually resistant to both X rays and ultraviolet (UV) photons. An understanding of how wild-type strains mutate and become more resistant should lead to a better understanding of DNA repair processes and their effects on radiation sensitivity.

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