Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1995 Oct;74(4):370-2.
doi: 10.1136/hrt.74.4.370.

Absence of circadian variation in the onset of acute myocardial infarction in diabetic subjects

S Fava  1 , J Azzopardi, H A Muscat, F F Fenech
Affiliations

Absence of circadian variation in the onset of acute myocardial infarction in diabetic subjects

S Fava et al. Br Heart J. 1995 Oct.

Abstract

Objectives: To investigate the circadian pattern of acute myocardial infarction in non-insulin-dependent diabetic patients and to compare it with that of controls.

Background: Previous studies have shown that there is a circadian variation in the incidence of acute myocardial infarction, but there are few data on diabetic subjects.

Methods: A hospital based prospective case-control study.

Results: 196 diabetic patients and 196 age and sex matched controls were admitted with a diagnosis of acute myocardial infarction during the study period. IN 32 diabetic patients and 38 controls, the time of onset of myocardial infarction was unknown; in 34, 44, 42, and 44 diabetic patients the onset was in the first to fourth quarters respectively (chi 2 = 1.66, NS). The corresponding figures for the controls were 30, 56, 45, and 27 (chi 2 = 13.9, P < 0.005). The difference between the two groups was highly significant (chi 2 = 10.3, P < 0.025).

Conclusions: Diabetic subjects do not show a significant circadian variation in the onset of acute myocardial infarction.

PubMed Disclaimer

References

    1. Biorheology. 1973 Dec;10(4):577-83 - PubMed
    1. Diabetes Care. 1993 Dec;16(12):1615-8 - PubMed
    1. Chest. 1982 Jun;81(6):681-6 - PubMed
    1. J Am Coll Cardiol. 1985 Mar;5(3):619-24 - PubMed
    1. J Hypertens. 1984 Apr;2(2):203-8 - PubMed