Results of single-agent and combination chemotherapy for advanced soft tissue sarcomas. Implications for decision making in the clinic
- PMID: 7490240
Results of single-agent and combination chemotherapy for advanced soft tissue sarcomas. Implications for decision making in the clinic
Abstract
Cytotoxic chemotherapy remains the principal modality of treating advanced or unresectable sarcomas of soft tissue. Certain drugs, such as doxorubicin and ifosfamide, are able to induce clinically useful antitumor effects as single agents, and combination chemotherapy regimens have been tested based upon these results. This article summarizes the results of single agent and combination chemotherapy trials for soft tissue sarcomas.
Similar articles
-
[Soft tissue sarcoma: postoperative chemotherapy].Gan To Kagaku Ryoho. 2004 Sep;31(9):1324-30. Gan To Kagaku Ryoho. 2004. PMID: 15446551 Review. Japanese.
-
Current perspectives in the management of soft-tissue sarcoma. The role of chemotherapy in multimodality therapy.Can J Surg. 1988 Nov;31(6):390-6. Can J Surg. 1988. PMID: 3052763 Review.
-
Management of soft tissue sarcomas of the extremity in adults.J Surg Oncol. 1996 Dec;63(4):271-9. doi: 10.1002/(SICI)1096-9098(199612)63:4<271::AID-JSO11>3.0.CO;2-6. J Surg Oncol. 1996. PMID: 8982374 Review.
-
Preoperative chemotherapy and split-course radiation therapy for patients with localized soft tissue sarcomas: home run, base hit, or strike out?J Clin Oncol. 2006 Feb 1;24(4):549-51. doi: 10.1200/JCO.2005.04.3026. J Clin Oncol. 2006. PMID: 16446327 No abstract available.
-
Phase II trial of neoadjuvant vincristine, ifosfamide, and doxorubicin with granulocyte colony-stimulating factor support in children and adolescents with advanced-stage nonrhabdomyosarcomatous soft tissue sarcomas: a Pediatric Oncology Group Study.J Clin Oncol. 2005 Jun 20;23(18):4031-8. doi: 10.1200/JCO.2005.03.209. Epub 2005 Mar 14. J Clin Oncol. 2005. PMID: 15767644 Clinical Trial.
Cited by
-
The "old drug" dacarbazine as a second/third line chemotherapy in advanced soft tissue sarcomas.Invest New Drugs. 2008 Apr;26(2):175-81. doi: 10.1007/s10637-007-9086-z. Epub 2007 Sep 25. Invest New Drugs. 2008. PMID: 17898927
-
ET-743.Drugs. 2002;62(8):1185-92; discussion 1193-4. doi: 10.2165/00003495-200262080-00005. Drugs. 2002. PMID: 12010079 Review.
-
Molecular features and vulnerabilities of recurrent chordomas.J Exp Clin Cancer Res. 2021 Jul 30;40(1):244. doi: 10.1186/s13046-021-02037-y. J Exp Clin Cancer Res. 2021. PMID: 34330313 Free PMC article.
-
Mesenchymal Chondrosarcoma in Children and Young Adults: A Single Institution Retrospective Review.Sarcoma. 2015;2015:608279. doi: 10.1155/2015/608279. Epub 2015 Jun 3. Sarcoma. 2015. PMID: 26146478 Free PMC article.
-
Pemetrexed in patients with refractory soft tissue sarcoma: a non-comparative multicenter phase II study of the German Sarcoma Group AIO-STS 005.Invest New Drugs. 2013 Feb;31(1):167-74. doi: 10.1007/s10637-012-9840-8. Epub 2012 Jul 5. Invest New Drugs. 2013. PMID: 22763609 Clinical Trial.
Publication types
MeSH terms
Substances
Supplementary concepts
LinkOut - more resources
Medical