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Clinical Trial
. 1995 Dec 2;346(8988):1464-5.
doi: 10.1016/s0140-6736(95)92475-2.

Transcutaneous oxygen levels in retinopathy of prematurity

S Cunningham  1 , B W Fleck, R A Elton, N McIntosh
Affiliations
Clinical Trial

Transcutaneous oxygen levels in retinopathy of prematurity

S Cunningham et al. Lancet. .

Abstract

Retinopathy of prematurity (ROP) is a potentially blinding disease of preterm infants. 21 days of computer-recorded transcutaneous oxygen (TcPO2) data were compared in 31 infants with stage 3 or greater ROP and 38 infants with no ROP or stage 1 or 2. In a multiple logistic regression adjusted for significant perinatal factors (birthweight, gestation, and intraventricular haemorrhage), babies with stage 3 or higher ROP showed an increased variability of TcPO2 in week 1 (p < 0.01) and 2 (p = 0.012) but not week 3. Variability of TcPO2 in the first 2 weeks of life is a significant predictor of severe ROP.

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