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Comparative Study
. 1995 Jul;39(7):1589-90.
doi: 10.1128/AAC.39.7.1589.

In vitro activity of the semisynthetic glycopeptide amide MDL 63,246

M T Kenny  1 , M A Brackman, J K Dulworth
Affiliations
Comparative Study

In vitro activity of the semisynthetic glycopeptide amide MDL 63,246

M T Kenny et al. Antimicrob Agents Chemother. 1995 Jul.

Abstract

The in vitro activity of the semisynthetic glycopeptide amide MDL 63,246 against 293 U.S. clinical isolates of gram-positive cocci was determined by the broth microdilution method. When compared with teicoplanin, MDL 63,246 had improved activity against Staphylococcus epidermidis (MICs that inhibited 90% strains tested [MIC90s], 0.25 versus 8 micrograms/ml, respectively). Staphylococcus haemolyticus (MIC90s, 1 versus 32 micrograms/ml, respectively), and VanA Enterococcus faecium (MIC90s, 32 versus > or = 1,024 micrograms/ml, respectively).

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