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. 1995 May;35(6):1189-98.

Polyamines exert regulatory control on mycobacterial transcription: a study using RNA polymerase from Mycobacterium phlei

N K Sarkar  1 , S Shankar, A K Tyagi
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  • PMID: 7492956

Polyamines exert regulatory control on mycobacterial transcription: a study using RNA polymerase from Mycobacterium phlei

N K Sarkar et al. Biochem Mol Biol Int. 1995 May.

Abstract

We have used purified RNA polymerase from Mycobacterium phlei to study the role of polyamines in mycobacterial transcription. Both initiation and elongation phases of the process were affected biphasically by polyamines. Interaction of polyamines with DNA template plays an important role in transcription modulation. Our studies emphasize that polyamines can exert a regulatory control on mycobacterial transcription.

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