Review
doi: 10.1016/0955-0674(95)80009-3.
Quality control in the secretory pathway
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- PMID: 7495572
- DOI: 10.1016/0955-0674(95)80009-3
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Review
Quality control in the secretory pathway
Curr Opin Cell Biol.
1995 Aug.
Abstract
Whereas newly synthesized proteins that have acquired a properly folded and assembled structure are transported from the endoplasmic reticulum to their final destinations, incompletely folded and assembled proteins are, as a rule, retained and eventually degraded. The molecular mechanisms of this unique molecular sorting phenomenon, called 'quality control', have been illuminated by recent studies.
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