Review
[Trophoblastic interferons and embryonal immune tolerance]
[Article in
French]
Affiliations
- PMID: 7496430
Item in Clipboard
Review
[Trophoblastic interferons and embryonal immune tolerance]
[Article in
French]
Contracept Fertil Sex.
1995 Sep.
Abstract
Current evidence support the hypothesis that trophoblast interferons play a key role in preventing maternal immunologal rejection of the embryonic semi-allograft. The information of this review is divided in two sections. In the first section we described molecular and biological characteristics of type I (alpha, beta, omega, tau and spl) and type II (gamma) interferons. In the second section we emphasize studies on immunoendocrine functions of IFN-tau (oTP-1 or trophoblastins) in the network of cytokines and hormonal environment at the uterine embryonic interface.
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