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. 1978 Dec;37(6):510-2.
doi: 10.1136/ard.37.6.510.

Spondylodiscitis and ankylosing spondylitis: HLA typing and nosological implications

Spondylodiscitis and ankylosing spondylitis: HLA typing and nosological implications

V Modena et al. Ann Rheum Dis. 1978 Dec.

Abstract

Nine cases from among 64 patients with ankylosing spondylitis (AS) are described. In addition to bilateral sacroiliitis these cases had a peculiar type of spondylodiscitis characterised by quite diffuse and marked sclerosis of multiple vertebral bodies, with only minimal erosions of the adjacent vertebral plates while classical syndesmophytosis was absent. The antigen HLA-B27 was found only in 1 of these 9 cases. This type of spondylodiscitis could discriminate among all the patients with AS a subgroup with a peculiar clinical pattern and a probably distinctive pathological mechanism.

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References

    1. J Radiol Electrol Arch Electr Medicale. 1956 Nov-Dec;37(11-12):887-93 - PubMed
    1. J Rheumatol Suppl. 1977;3:5-10 - PubMed
    1. J Rheumatol Suppl. 1977;3:18-23 - PubMed
    1. Rev Rhum Mal Osteoartic. 1977 Jan;44(1):17-25 - PubMed
    1. Ann Rheum Dis. 1972 Sep;31(5):345-58 - PubMed