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Review
. 1993 Oct;3(5):713-8.
doi: 10.1016/s0959-437x(05)80088-7.

The retron: a bacterial retroelement required for the synthesis of msDNA

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Review

The retron: a bacterial retroelement required for the synthesis of msDNA

S Inouye et al. Curr Opin Genet Dev. 1993 Oct.

Abstract

'Retrons' are bacterial retroelements responsible for the synthesis of msDNA, a hybrid nucleic acid consisting of a single-stranded DNA that is branched out from an internal guanosine of an RNA molecule via a 2',5'-phosphodiester linkage. Retrons are found in a minor population of various bacterial species and are extensively diverse. Two important questions now demanding attention are whether retrons are mobile elements and why are they so diverse?

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