Clinical Trial
doi: 10.2165/00003495-199300461-00037.
Nimesulide in the treatment of advanced cancer pain. Double-blind comparison with naproxen
Affiliations
- PMID: 7506159
- DOI: 10.2165/00003495-199300461-00037
Item in Clipboard
Clinical Trial
Nimesulide in the treatment of advanced cancer pain. Double-blind comparison with naproxen
Drugs.
1993.
Abstract
The analgesic efficacy and tolerability of nimesulide and naproxen were compared in 68 patients with advanced cancer who needed to be treated with nonsteroidal anti-inflammatory drugs according to the first step of the pharmacological analgesic scale of the WHO. Patients received either nimesulide 200mg or naproxen 500mg twice daily. The analgesic efficacy and tolerability of the 2 drugs appeared to be similar. Both drugs were effective and were associated with a low incidence of adverse reactions.
Similar articles
-
Nimesulide in the treatment of advanced cancer pain. Double-blind comparison with naproxen.Arzneimittelforschung. 1992 Aug;42(8):1028-30. Arzneimittelforschung. 1992. PMID: 1418076 Clinical Trial.
-
A randomized, double-blind, multicenter trial of nimesulide-beta-cyclodextrin versus naproxen in patients with osteoarthritis.Clin Ther. 2002 Apr;24(4):504-19. doi: 10.1016/s0149-2918(02)85127-x. Clin Ther. 2002. PMID: 12017396 Clinical Trial.
-
Clinical efficacy and tolerability of nimesulide compared with naproxen in the treatment of posthaemorrhoidectomy pain and inflammation.Drugs. 1993;46 Suppl 1:177-9. doi: 10.2165/00003495-199300461-00043. Drugs. 1993. PMID: 7506165 Clinical Trial.
-
Nimesulide. A preliminary review of its pharmacological properties and therapeutic efficacy in inflammation and pain states.Drugs. 1988 Dec;36(6):732-53. doi: 10.2165/00003495-198836060-00004. Drugs. 1988. PMID: 3065059 Review.
-
Nimesulide, a balanced drug for the treatment of osteoarthritis.Clin Exp Rheumatol. 2001;19(1 Suppl 22):S21-5. Clin Exp Rheumatol. 2001. PMID: 11296545 Review.
Cited by
-
Oral nonsteroidal anti-inflammatory drugs (NSAIDs) for cancer pain in adults.Cochrane Database Syst Rev. 2017 Jul 12;7(7):CD012638. doi: 10.1002/14651858.CD012638.pub2. Cochrane Database Syst Rev. 2017. PMID: 28700091 Free PMC article.
-
A pilot study of acupuncture at pain acupoints for cervical cancer pain.Medicine (Baltimore). 2018 Dec;97(52):e13736. doi: 10.1097/MD.0000000000013736. Medicine (Baltimore). 2018. PMID: 30593148 Free PMC article.
-
Nonsteroidal anti-inflammatory drugs and pain in cancer patients: a systematic review and reappraisal of the evidence.Br J Anaesth. 2019 Aug;123(2):e412-e423. doi: 10.1016/j.bja.2019.02.028. Epub 2019 May 20. Br J Anaesth. 2019. PMID: 31122736 Free PMC article.
-
Systematic review and meta-analysis on non-opioid analgesics in palliative medicine.J Cachexia Sarcopenia Muscle. 2018 Dec;9(7):1235-1254. doi: 10.1002/jcsm.12352. Epub 2018 Oct 29. J Cachexia Sarcopenia Muscle. 2018. PMID: 30375188 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
