Tolerability of nimesulide and ketoprofen in paediatric patients with traumatic or surgical fractures
- PMID: 7506182
- DOI: 10.2165/00003495-199300461-00061
Tolerability of nimesulide and ketoprofen in paediatric patients with traumatic or surgical fractures
Abstract
The anti-inflammatory and analgesic activities of orally administered nimesulide and ketoprofen were assessed in a group of 71 paediatric patients (aged 7 to 14 years) with orthopaedic disorders. Both drugs had similar efficacy. The greatest advantage of nimesulide was its better tolerability: only 3 nimesulide-treated patients (8.6%) experienced side effects related to the drug, compared with 12 (33%) of the ketoprofen-treated children.
Similar articles
-
A double-blind comparison of nimesulide and ketoprofen in dental surgery.Drugs. 1993;46 Suppl 1:168-70. doi: 10.2165/00003495-199300461-00040. Drugs. 1993. PMID: 7506162 Clinical Trial.
-
Nimesulide in the treatment of osteoarthritis. Double-blind studies in comparison with piroxicam, ketoprofen and placebo.Drugs. 1993;46 Suppl 1:191-5. doi: 10.2165/00003495-199300461-00048. Drugs. 1993. PMID: 7506169 Clinical Trial.
-
Comparative efficacy of nimesulide and ketoprofen on inflammatory events in third molar surgery: a split-mouth, prospective, randomized, double-blind study.Int J Oral Maxillofac Surg. 2015 Jul;44(7):876-84. doi: 10.1016/j.ijom.2014.10.026. Epub 2015 Apr 3. Int J Oral Maxillofac Surg. 2015. PMID: 25847016 Clinical Trial.
-
Nimesulide. A preliminary review of its pharmacological properties and therapeutic efficacy in inflammation and pain states.Drugs. 1988 Dec;36(6):732-53. doi: 10.2165/00003495-198836060-00004. Drugs. 1988. PMID: 3065059 Review.
-
Pain and ketoprofen: what is its role in clinical practice?Reumatismo. 2010 Jul-Sep;62(3):172-88. doi: 10.4081/reumatismo.2010.172. Reumatismo. 2010. PMID: 21052564 Review.
Cited by
-
Nimesulide. An update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.Drugs. 1994 Sep;48(3):431-54. doi: 10.2165/00003495-199448030-00009. Drugs. 1994. PMID: 7527762 Review.
-
Antipyretic Use in Noncritically Ill Patients With Fever: A Review.Cureus. 2024 Jan 9;16(1):e51943. doi: 10.7759/cureus.51943. eCollection 2024 Jan. Cureus. 2024. PMID: 38333494 Free PMC article. Review.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical