doi: 10.1097/00001756-199312000-00018.
Expression of 25(OH) vitamin D3 24-hydroxylase gene in glial cells
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- PMID: 7507724
- DOI: 10.1097/00001756-199312000-00018
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Expression of 25(OH) vitamin D3 24-hydroxylase gene in glial cells
Neuroreport.
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Abstract
The expression of the 25(OH) vitamin D3 24-hydroxylase gene was studied in C6 glioma and rat primary glial cell culture. The expression of the 25(OH)D3 24-hydroxylase gene was not detected in C6 glioma or glial cells cultured in a serum-free medium. However, the 25(OH)D3 24-hydroxylase mRNA was induced in a dose-dependent manner in cells treated with 1,25(OH)2D3. These findings provide further evidence for an involvement of vitamin D3 metabolites in brain function.
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