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. 1993 Dec 13;5(3):255-7.
doi: 10.1097/00001756-199312000-00018.

Expression of 25(OH) vitamin D3 24-hydroxylase gene in glial cells

P Naveilhan  1 , I Neveu, C Baudet, K Y Ohyama, P Brachet, D Wion
Affiliations

Expression of 25(OH) vitamin D3 24-hydroxylase gene in glial cells

P Naveilhan et al. Neuroreport. .

Abstract

The expression of the 25(OH) vitamin D3 24-hydroxylase gene was studied in C6 glioma and rat primary glial cell culture. The expression of the 25(OH)D3 24-hydroxylase gene was not detected in C6 glioma or glial cells cultured in a serum-free medium. However, the 25(OH)D3 24-hydroxylase mRNA was induced in a dose-dependent manner in cells treated with 1,25(OH)2D3. These findings provide further evidence for an involvement of vitamin D3 metabolites in brain function.

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