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Comparative Study
. 1993 Dec;31(12):3184-9.
doi: 10.1128/jcm.31.12.3184-3189.1993.

Differentiation of U.S. and European isolates of porcine reproductive and respiratory syndrome virus by monoclonal antibodies

E A Nelson  1 , J Christopher-Hennings, T Drew, G Wensvoort, J E Collins, D A Benfield
Affiliations
Comparative Study

Differentiation of U.S. and European isolates of porcine reproductive and respiratory syndrome virus by monoclonal antibodies

E A Nelson et al. J Clin Microbiol. 1993 Dec.

Abstract

Monoclonal antibodies (MAbs) to two U.S. isolates of porcine reproductive and respiratory syndrome (PRRS) virus were prepared. Two MAbs specifically recognized a conserved epitope on the putative 15-kDa nucleocapsid protein of U.S. and European isolates of PRRS virus. Four other MAbs recognized epitopes on the 15-kDa protein of U.S. but not European isolates of PRRS virus. Collectively, this indicates that PRRS viruses contain both conserved and divergent epitopes on the 15-kDa viral protein.

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