Calcineurin is a key signaling enzyme in T lymphocyte activation and the target of the immunosuppressive drugs cyclosporin A and FK506
- PMID: 7509131
- DOI: 10.1111/j.1749-6632.1993.tb17138.x
Calcineurin is a key signaling enzyme in T lymphocyte activation and the target of the immunosuppressive drugs cyclosporin A and FK506
Similar articles
-
Calcineurin mutants render T lymphocytes resistant to cyclosporin A.Mol Pharmacol. 1996 Sep;50(3):506-11. Mol Pharmacol. 1996. PMID: 8794888
-
The immunosuppressive drugs cyclosporin A and FK506 inhibit calcineurin phosphatase activity and gene transcription mediated through the cAMP-responsive element in a nonimmune cell line.Naunyn Schmiedebergs Arch Pharmacol. 1993 Nov;348(5):541-5. doi: 10.1007/BF00173216. Naunyn Schmiedebergs Arch Pharmacol. 1993. PMID: 7509460
-
Cyclosporin A inhibits 2-chloroadenosine-induced DNA cleavage in mouse thymocytes.Int J Immunopharmacol. 1994 Dec;16(12):995-1001. doi: 10.1016/0192-0561(94)90078-7. Int J Immunopharmacol. 1994. PMID: 7705972
-
[Multiple actions of tacrolimus and cyclosporin A as specific inhibitors of calcineurin].Tanpakushitsu Kakusan Koso. 1998 Jun;43(8 Suppl):1118-30. Tanpakushitsu Kakusan Koso. 1998. PMID: 9655970 Review. Japanese. No abstract available.
-
FK-506 and cyclosporin A: immunosuppressive mechanism of action and beyond.Curr Opin Immunol. 1992 Oct;4(5):548-52. doi: 10.1016/0952-7915(92)90024-9. Curr Opin Immunol. 1992. PMID: 1384551 Review.
Cited by
-
Nerve regeneration in rat limb allografts: evaluation of acute rejection rescue.Plast Reconstr Surg. 2013 Apr;131(4):499e-511e. doi: 10.1097/PRS.0b013e31828275b7. Plast Reconstr Surg. 2013. PMID: 23542267 Free PMC article.
-
PP2B-dependent NO production in the medullary thick ascending limb during diabetes.Am J Physiol Renal Physiol. 2009 Aug;297(2):F471-80. doi: 10.1152/ajprenal.90760.2008. Epub 2009 May 20. Am J Physiol Renal Physiol. 2009. PMID: 19458119 Free PMC article.
-
Immunotherapy with tacrolimus (FK506) does not select for resistance to calcineurin inhibitors in Candida albicans isolates from liver transplant patients.Antimicrob Agents Chemother. 2006 Apr;50(4):1573-7. doi: 10.1128/AAC.50.4.1573-1577.2006. Antimicrob Agents Chemother. 2006. PMID: 16569889 Free PMC article.
-
Signal Transduction in Leaf Movement.Plant Physiol. 1995 Nov;109(3):729-734. doi: 10.1104/pp.109.3.729. Plant Physiol. 1995. PMID: 12228627 Free PMC article. No abstract available.
-
Calcineurin signaling as a target for the treatment of alcohol abuse and neuroinflammatory disorders.Prog Mol Biol Transl Sci. 2019;167:125-142. doi: 10.1016/bs.pmbts.2019.06.008. Epub 2019 Aug 12. Prog Mol Biol Transl Sci. 2019. PMID: 31601401 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources