NusA changes the conformation of Escherichia coli RNA polymerase at the binding site for the 3' end of the nascent RNA
- PMID: 7510675
- PMCID: PMC205271
- DOI: 10.1128/jb.176.6.1787-1789.1994
NusA changes the conformation of Escherichia coli RNA polymerase at the binding site for the 3' end of the nascent RNA
Abstract
A conformational change in Escherichia coli RNA polymerase induced by NusA was detected by utilizing photocrosslinking. A change in the binding site for the 3' end of the RNA occurred, and NusA increased interactions of the RNA with the beta subunit of the polymerase. NusA was not contacted by the 3' end of the RNA.
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