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Case Reports
. 1994 Mar;43(3):408-10.
doi: 10.1016/0090-4295(94)90092-2.

Prostate-specific antigen decline after casodex withdrawal: evidence for an antiandrogen withdrawal syndrome

E J Small  1 , P R Carroll
Affiliations
Case Reports

Prostate-specific antigen decline after casodex withdrawal: evidence for an antiandrogen withdrawal syndrome

E J Small et al. Urology. 1994 Mar.

Abstract

Objective: To evaluate the relationship between antiandrogen withdrawal and change in prostate-specific antigen (PSA) when the antiandrogen in question is other than flutamide.

Methods: Presented is a case of a patient in whom the antiandrogen casodex was discontinued after clinical progression despite combined androgen blockade.

Results: A transient decline in serum PSA was observed after casodex withdrawal.

Conclusions: The relationship between antiandrogen withdrawal and a change in PSA may be a general phenomenon, not unique to flutamide.

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