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. 1978 Feb 15;34(2):158-9.
doi: 10.1007/BF01944649.

Hypotensive activity of some dihydroxycoumarins and their congeners

Hypotensive activity of some dihydroxycoumarins and their congeners

R S Thakur et al. Experientia. .

Abstract

Evaluation of the hypotensive activity of dihydroxy coumarins and their congeners reveal that the naturally occurring dimethoxy coumarin Scoparone has maximal activity, more significant than L-alpha-methyl dopa. Structure activity relationship studies are reported with an attempt to offer a probable mechanism of action.

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    1. J Med Chem. 1974 May;17(5):565-8 - PubMed
    1. J Med Chem. 1970 Nov;13(6):1226-7 - PubMed

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