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Review
. 1994 Jun;91(2-3):199-205.
doi: 10.1016/0009-2797(94)90040-x.

Selenium in the maintenance and therapy of HIV-infected patients

G N Schrauzer  1 , J Sacher
Affiliations
Review

Selenium in the maintenance and therapy of HIV-infected patients

G N Schrauzer et al. Chem Biol Interact. 1994 Jun.

Erratum in

  • Chem Biol Interact 1995 Feb;94(2):167

Abstract

Due to its antiviral effects and its importance for all immunological functions, the administration of selenium is suggested as a supportive measure in early as well as in advanced stages of HIV-induced disease. Initial observations on the effects of selenium supplementation in HIV-infected patients indicate that selenium causes symptomatic improvements and possibly slows the course of the disease. As selenium inhibits reverse transcriptase activity in RNA-virus-infected animals, supplemental selenium could also prevent the replication of HIV and retard the development of AIDS in newly HIV-infected subjects. An adequate supply of selenium and of antioxidant vitamins is also proposed as a measure to reduce the probability of the placental transmission of HIV in pregnancy.

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