doi: 10.1016/0165-1161(94)90033-7.
Human micronucleus counts are correlated with age, smoking, and cesium-137 dose in the Goiânia (Brazil) radiological accident
Affiliations
- PMID: 7519311
- DOI: 10.1016/0165-1161(94)90033-7
Item in Clipboard
Human micronucleus counts are correlated with age, smoking, and cesium-137 dose in the Goiânia (Brazil) radiological accident
Mutat Res.
1994 Aug.
Abstract
A random sample of 276 people representing control, direct exposure, and probable indirect exposure in the Goiânia, Brazil radiological accident was examined using micronuclei as indicators of cytogenetic damage. The Goiânia subjects were analyzed for interactions of age, lifestyle, and ionizing radiation dose. Increases in micronucleus frequencies were most strongly correlated with the dose of ionizing radiation, but age, alcohol consumption, and smoking habits also affected micronucleus frequencies. Despite these additional influences, micronucleus frequencies can be useful as biological dosimeters.
Similar articles
-
Lessons from the accident with 137Cesium in Goiania, Brazil: Contributions to biological dosimetry in case of human exposure to ionizing radiation.Mutat Res Genet Toxicol Environ Mutagen. 2018 Dec;836(Pt A):72-77. doi: 10.1016/j.mrgentox.2018.05.019. Epub 2018 May 28. Mutat Res Genet Toxicol Environ Mutagen. 2018. PMID: 30389165
-
The fate of chromosomal aberrations in 137Cs-exposed individuals in the Goiânia radiation accident.Health Phys. 1991 Jan;60(1):67-70. doi: 10.1097/00004032-199101000-00010. Health Phys. 1991. PMID: 1983985
-
Orofacial manifestations from accidental exposure to caesium 137 in Goiania, Brazil.J Oral Pathol Med. 1990 Aug;19(7):322-5. doi: 10.1111/j.1600-0714.1990.tb00853.x. J Oral Pathol Med. 1990. PMID: 2231437
-
Follow-up studies on genome damage in children after Chernobyl nuclear power plant accident.Arch Toxicol. 2016 Sep;90(9):2147-2159. doi: 10.1007/s00204-016-1766-z. Epub 2016 Jun 22. Arch Toxicol. 2016. PMID: 27329326 Review.
-
Current cytogenetic methods for detecting exposure and effects of mutagens and carcinogens.Environ Health Perspect. 1996 May;104 Suppl 3(Suppl 3):445-8. doi: 10.1289/ehp.96104s3445. Environ Health Perspect. 1996. PMID: 8781361 Free PMC article. Review.
Cited by
-
Baseline micronuclei frequency in children: estimates from meta- and pooled analyses.Environ Health Perspect. 2005 Sep;113(9):1226-9. doi: 10.1289/ehp.7806. Environ Health Perspect. 2005. PMID: 16140632 Free PMC article.
-
The RABiT: a rapid automated biodosimetry tool for radiological triage. II. Technological developments.Int J Radiat Biol. 2011 Aug;87(8):776-90. doi: 10.3109/09553002.2011.573612. Epub 2011 May 11. Int J Radiat Biol. 2011. PMID: 21557703 Free PMC article.
-
Establishment of ex vivo calibration curve for X-ray induced "dicentric + ring" and micronuclei in human peripheral lymphocytes for biodosimetry during radiological emergencies, and validation with dose blinded samples.Heliyon. 2023 Jun 7;9(6):e17068. doi: 10.1016/j.heliyon.2023.e17068. eCollection 2023 Jun. Heliyon. 2023. PMID: 37484390 Free PMC article.
-
The RABIT: a rapid automated biodosimetry tool for radiological triage.Health Phys. 2010 Feb;98(2):209-17. doi: 10.1097/HP.0b013e3181ab3cb6. Health Phys. 2010. PMID: 20065685 Free PMC article.
-
Factors Affecting the Nuclei in Newborn and Children.Int J Environ Res Public Health. 2022 Apr 1;19(7):4226. doi: 10.3390/ijerph19074226. Int J Environ Res Public Health. 2022. PMID: 35409906 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
