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. 1994 Jul 30;29(5):1011-4.
doi: 10.1016/0360-3016(94)90396-4.

Retreatment with radiotherapy for painful bone metastases

N P Mithal  1 , P R Needham, P J Hoskin
Affiliations

Retreatment with radiotherapy for painful bone metastases

N P Mithal et al. Int J Radiat Oncol Biol Phys. .

Abstract

Purpose: To evaluate the response to reirradiation of painful bone metastases following initial treatment with radiotherapy.

Methods and materials: A retrospective analysis of 105 consecutive patients treated with palliative radiotherapy for painful bone metastases. A total of 280 individual treatment sites were identified, of which 57 were retreated once and 8 were retreated twice.

Results: The overall response rate to initial treatment was 84% for pain relief, and at first retreatment this was 87%. Seven of eight patients retreated a second time also achieved pain relief. No relation to radiation dose, primary tumor type, or site was seen.

Conclusions: In patients relapsing after radiotherapy to painful bone metastases who have responded initially, reirradiation can be recommended with a similar probability of response.

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