[Evaluation of treatment efficiency of acute hemispheric strokes using intravenous nimodipine infusions]

Abstract

The authors present the results of treating acute hemispheric stroke with intravenous nimodipine. 17 patients were additionally treated with nimodipine given intravenously in 1 mg-2 mg dose, and the control group consisted of 71 patients treated in standard way with Dextran 40,000. The selection of patients for the study was random, and the treatment was conducted by blind trial method. All patients were admitted within 24 hours since acute stroke onset. The diagnosis was based on clinical examination and CT. The analysis of treatment results was made twice before and after the treatment according to criteria recommended by WHO Karnofsky scale. Statistical analysis showed that in the group treated additionally with nimodipine neurological and social consequences of stroke were significantly lower in comparison with standard therapy (p < 0.001).