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. 1994;48(1):3-5.
doi: 10.1016/0753-3322(94)90183-x.

Changes in the level of blood suppressor CD8+CD57+ lymphocytes, when HIV-1 p24 antigen reappears in the blood

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Changes in the level of blood suppressor CD8+CD57+ lymphocytes, when HIV-1 p24 antigen reappears in the blood

G Mathé et al. Biomed Pharmacother. 1994.

Abstract

Using the marker Leu2 + Leu7 + to detect the CD8 suppressor cells (CD88+CD57+), we have observed that their blood level, which increases after primoinfection, during the latent period, increases still further just before and when the p24 antigen returns and is present in the blood. Its ratio over cytotoxic CD8+ cells remains high during the AIDS period, though the absolute number decreases.

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