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. 1994 Nov;70(5):799-803.
doi: 10.1038/bjc.1994.402.

Identification of glioma-associated antigen MUC 2-63 as CD44

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Free PMC article

Identification of glioma-associated antigen MUC 2-63 as CD44

P Romeijn et al. Br J Cancer. 1994 Nov.
Free PMC article

Abstract

Monoclonal antibody MUC 2-63 recognises neurogenic tumours and has been used successfully for radioimaging human malignant gliomas. We now show that the MUC 2-63 antigen has the same tissue distribution and molecular weight range as the CD44 antigen and confirm the identity of these two molecules in blocking studies using MUC 2-63 and the CD44 anti-framework antibody F10-44-2. Thus not only MUC 2-63 but also other anti-CD44 monoclonal antibodies should prove useful in imaging and, perhaps, therapy of brain tumours.

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References

    1. Dev Immunol. 1994;3(4):239-46 - PubMed
    1. J Cell Biol. 1993 Jul;122(2):431-42 - PubMed
    1. Proc Natl Acad Sci U S A. 1979 Sep;76(9):4350-4 - PubMed
    1. Eur J Immunol. 1980 Oct;10(10):745-9 - PubMed
    1. J Neurochem. 1982 Nov;39(5):1461-6 - PubMed

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