doi: 10.1007/BF00312923.
Crossed immunoelectrofocusing of cerebrospinal fluid immunoglobulins
- PMID: 75256
- DOI: 10.1007/BF00312923
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Crossed immunoelectrofocusing of cerebrospinal fluid immunoglobulins
J Neurol.
.
Abstract
The combination of the high separation capacity of isoelectric focusing and the specificity of immunoelectrophoresis gives a valuable tool for protein studies. This technic can be applied to immunoglobulin examinations by using KOCN-treated antibodies isoelectric at pH 5 and performing the immunoelectrophoretic procedure at this pH. CSF and serum samples of patients exhibiting CSF immunoglobulin abnormalities and blood-CSF barrier damages were examined by this method.
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