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. 1977 Dec 13;217(2):103-9.
doi: 10.1007/BF00312923.

Crossed immunoelectrofocusing of cerebrospinal fluid immunoglobulins

A Sidén

Crossed immunoelectrofocusing of cerebrospinal fluid immunoglobulins

A Sidén. J Neurol. .

Abstract

The combination of the high separation capacity of isoelectric focusing and the specificity of immunoelectrophoresis gives a valuable tool for protein studies. This technic can be applied to immunoglobulin examinations by using KOCN-treated antibodies isoelectric at pH 5 and performing the immunoelectrophoretic procedure at this pH. CSF and serum samples of patients exhibiting CSF immunoglobulin abnormalities and blood-CSF barrier damages were examined by this method.

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References

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