Direct detection of the Philadelphia chromosome in CD20-positive lymphocytes in chronic myeloid leukemia by tri-color immunophenotyping/FISH
- PMID: 7526092
Direct detection of the Philadelphia chromosome in CD20-positive lymphocytes in chronic myeloid leukemia by tri-color immunophenotyping/FISH
Abstract
Six patients with previously diagnosed chronic myelogenous leukemia (CML) were studied by a tri-color immunophenotyping/FISH method for direct determination of the Philadelphia (Ph) chromosome in B and T lymphocytes. Two patients had involvement of CD20-positive lymphocytes. CD3-positive lymphocytes in all patients were negative for the Ph chromosome.
Comment in
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Flow cytometric detection of B cell abnormal maturation in chronic myeloid leukemia.Leukemia. 2000 Feb;14(2):339-40. doi: 10.1038/sj.leu.2401549. Leukemia. 2000. PMID: 10673756 No abstract available.
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