Acute reversible ataxo-myoclonic encephalopathy with flecainide therapy
- PMID: 7526455
Acute reversible ataxo-myoclonic encephalopathy with flecainide therapy
Abstract
A 73 year-old patient with Wolff-Parkinson-White syndrome and paroxysmic supraventricular tachycardia developed an acute reversible encephalopathy within 15 days of initiation of flecainide. The clinical picture was characterized by visual hallucinations, agitation, anxiety, but no disorientation, and a severe cerebello-myoclonic syndrome with total inability to stand up and walk, which was fully reversible on discontinuing the medication.
Similar articles
-
[Use of flecainide in the preventive treatment of tachycardia crisis of Wolff-Parkinson-White syndrome in 4 newborn infants].Arch Fr Pediatr. 1991 Nov;48(9):627-9. Arch Fr Pediatr. 1991. PMID: 1763931 French.
-
Flecainide and sotalol: a new combination therapy for refractory supraventricular tachycardia in children <1 year of age.J Am Coll Cardiol. 2002 Feb 6;39(3):517-20. doi: 10.1016/s0735-1097(01)01773-9. J Am Coll Cardiol. 2002. PMID: 11823091
-
ECGs in the ED.Pediatr Emerg Care. 2008 Nov;24(11):803-4. doi: 10.1097/PEC.0b013e318191ab95. Pediatr Emerg Care. 2008. PMID: 19018229 No abstract available.
-
[Drug therapy of supraventricular and ventricular tachyarrhythmias].Internist (Berl). 1996 Jan;37(1):45-52. Internist (Berl). 1996. PMID: 8837827 Review. German. No abstract available.
-
[Flecainide and anti-arrhythmia therapy].Minerva Med. 1988 Mar;79(3):229-34. Minerva Med. 1988. PMID: 3129677 Review. Italian.
Cited by
-
When potion becomes poison! A case report of flecainide toxicity.J Postgrad Med. 2017 Oct-Dec;63(4):265-267. doi: 10.4103/0022-3859.201422. J Postgrad Med. 2017. PMID: 28272074 Free PMC article.
-
Safety of flecainide.Drug Saf. 2012 Apr 1;35(4):273-89. doi: 10.2165/11599950-000000000-00000. Drug Saf. 2012. PMID: 22435343 Review.
-
Drug-induced myoclonus: frequency, mechanisms and management.CNS Drugs. 2004;18(2):93-104. doi: 10.2165/00023210-200418020-00003. CNS Drugs. 2004. PMID: 14728056 Review.
-
Drug-induced movement disorders.Drug Saf. 1997 Mar;16(3):180-204. doi: 10.2165/00002018-199716030-00004. Drug Saf. 1997. PMID: 9098656 Review.
-
A rare case of flecainide-induced encephalopathy.HeartRhythm Case Rep. 2023 Dec 21;10(3):201-202. doi: 10.1016/j.hrcr.2023.12.008. eCollection 2024 Mar. HeartRhythm Case Rep. 2023. PMID: 38496743 Free PMC article. No abstract available.