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Comparative Study
. 1994;135(3-4):433-5.
doi: 10.1007/BF01310027.

Differences in antigenicity of E2 in Semliki Forest virus particles and in infected cells

S Repges-Illguth  1 , G Kaluza
Affiliations
Comparative Study

Differences in antigenicity of E2 in Semliki Forest virus particles and in infected cells

S Repges-Illguth et al. Arch Virol. 1994.

Abstract

Using six monoclonal antibodies to epitopes a-f on the glycoprotein E2 of Semliki Forest virus (SFV) we found antigenic differences between E2 in infected cells and in virus particles, respectively, if glycosylation was impaired by 2-deoxy-D-glucose or inhibited by N-methyl-1-deoxynojirimycin. Furthermore we concluded that a conformational change of E2 takes place on virus budding.

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References

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