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Comparative Study
. 1995 Jan;177(1):264-7.
doi: 10.1128/jb.177.1.264-267.1995.

The role of ribonuclease H in multicopy single-stranded DNA synthesis in retron-Ec73 and retron-Ec107 of Escherichia coli

T Shimamoto  1 , M Shimada, M Inouye, S Inouye
Affiliations
Comparative Study

The role of ribonuclease H in multicopy single-stranded DNA synthesis in retron-Ec73 and retron-Ec107 of Escherichia coli

T Shimamoto et al. J Bacteriol. 1995 Jan.

Abstract

Bacterial reverse transcriptase is responsible for the synthesis of multicopy single-stranded DNA (msDNA). Reverse transcriptases from retron-Ec73 and retron-Ec107 do not contain an RNase H domain. Cellular RNase H is therefore considered to be required to make the mature form of msDNA. We found that RNase HI, but not RNase HII, is required for the production of the mature form of both msDNAs.

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References

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