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. 1994 Aug;102(2):89-92.
doi: 10.1007/BF00269011.

Localization of nitric oxide synthase immunoreactivity in mast cells of human nasal mucosa

S Bacci  1 , R Arbi-Riccardi, B Mayer, C Rumio, M B Borghi-Cirri
Affiliations

Localization of nitric oxide synthase immunoreactivity in mast cells of human nasal mucosa

S Bacci et al. Histochemistry. 1994 Aug.

Abstract

Nitric oxide (NO)-synthase immunoreactivity has been detected for the first time in mast cells of human normal nasal mucosa, with an antibody specific for neuronal NO-synthase. Intense immunoreactivity was revealed in secretion granules of mast cells but was found in mast cell granules free in the extracellular matrix only in some instances; no reactivity was found in the cytoplasm of this or other cell types. These findings suggest that human nasal mast cells contain a particulate isoform of NO-synthase, which shares epitopes with neuronal NO-synthase and is rapidly removed from granules upon exocytosis.

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References

    1. Proc Natl Acad Sci U S A. 1991 Mar 1;88(5):1788-92 - PubMed
    1. Nature. 1988 Jun 16;333(6174):664-6 - PubMed
    1. APMIS. 1993 Apr;101(4):330-6 - PubMed
    1. J Histochem Cytochem. 1985 Jan;33(1):27-32 - PubMed
    1. Exp Cell Res. 1965 Dec;40(3):637-54 - PubMed

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