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. 1995 Feb;194(2):545-9.
doi: 10.1148/radiology.194.2.7529936.

Carcinoma of the prostate: race as a prognostic indicator in definitive radiation therapy

J A Kim  1 , D A Kuban, A M el-Mahdi, P F Schellhammer
Affiliations

Carcinoma of the prostate: race as a prognostic indicator in definitive radiation therapy

J A Kim et al. Radiology. 1995 Feb.

Abstract

Purpose: To characterize the racial differences in prognostic factors and treatment outcome for patients undergoing radiation therapy for carcinoma of the prostate.

Materials and methods: From January 1975 through December 1989, 489 white and 157 black men with carcinoma of the prostate underwent irradiation. Factors analyzed were patient age, tumor stage and grade, prostate-specific antigen (PSA) levels, and disease-control and survival rates.

Results: More black patients than white patients were found to have poorly differentiated tumors. Black patients had higher PSA levels before and after treatment, resulting in a higher distant failure rate and poorer overall, cause-specific, and disease-free survival rates.

Conclusion: Black men have more aggressive prostatic tumors, a higher rate of metastasis, and a poorer survival rate than do white men.

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