Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Sep-Oct;20(5):664-70.

[Possible interference between tetanus toxin and organo-phosphorus esters in blocking of cholinesterase]

[Article in Italian]
  • PMID: 753135

[Possible interference between tetanus toxin and organo-phosphorus esters in blocking of cholinesterase]

[Article in Italian]
G Leonardi et al. Ann Sclavo. 1978 Sep-Oct.

Abstract

As tetanus toxin results inactivated when mixed with mammals brain homogenate (Wassermann-Takaki phenomenon), the same may be observed for the organophosphorus compounds. When the brain homogenates are mixed before with one of both poisons and subsequently, after incubation, with the other, this one keeps its typical toxic activity. This behavior seems to be interpreted as the result from the linkage between the true cholinesterase and one toxic (Wassermann-Takaki phenomenon both for the tetanus toxin and the "parathion"), with the following interference for the second toxic, when added, at the enzymatic level, so that the second toxic remains free.

PubMed Disclaimer

Similar articles

Publication types

LinkOut - more resources