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. 1995 Feb 13;359(2-3):247-50.
doi: 10.1016/0014-5793(95)00054-d.

Systemic production of foreign peptides on the particle surface of tobacco mosaic virus

Y Sugiyama  1 , H Hamamoto, S Takemoto, Y Watanabe, Y Okada
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Free article

Systemic production of foreign peptides on the particle surface of tobacco mosaic virus

Y Sugiyama et al. FEBS Lett. .
Free article

Abstract

By using a new tobacco mosaic virus (TMV) vector [Hamamoto, H., et al. (1993) Bio/Technology 11, 930-932], we have constructed TMV particles which present three different kinds of epitopes, two of them from influenza virus hemagglutinin (HA), and one from human immunodeficiency virus type I (HIV-I) envelope protein, on the surface of the particles. Each of these TMV particles reacted with each anti-peptide antiserum. These results suggest that this TMV vector can be used as an antigen presentation system.

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