Review
Pharmacotherapy of schizophrenia: a review
Affiliations
- PMID: 7533053
Item in Clipboard
Review
Pharmacotherapy of schizophrenia: a review
Can J Psychiatry.
1994 Nov.
Abstract
Traditional antipsychotic medications have targeted the dopamine system. Yet, the isolation and cloning of multiple dopamine receptor subtypes and the recognition of non-dopaminergic pathways (for example, serotonin) in schizophrenia have led to the development of new pharmacological strategies in pharmacotherapy. The author summarizes recent biochemical and pharmacological data and the clinical experience with novel antischizophrenic compounds.
Similar articles
-
Novel neuroleptics in schizophrenia: theory and clinical relevance.Can J Psychiatry. 1994 Nov;39(9 Suppl 2):S43-5. Can J Psychiatry. 1994. PMID: 7533050 No abstract available.
-
Pathophysiology and treatment of negative symptoms.Can J Psychiatry. 1994 Nov;39(9 Suppl 2):S53-8. Can J Psychiatry. 1994. PMID: 7533052 Review.
-
Risperidone: neurochemical, pharmacologic and clinical properties of a new antipsychotic drug.Can J Psychiatry. 1994 Nov;39(9 Suppl 2):S46-52. Can J Psychiatry. 1994. PMID: 7533051 Review.
-
The new atypical antipsychotics. A lack of extrapyramidal side-effects and new routes in schizophrenia research.Br J Psychiatry. 1994 Feb;164(2):141-8. doi: 10.1192/bjp.164.2.141. Br J Psychiatry. 1994. PMID: 7513599 Review. No abstract available.
-
New antipsychotic medications: do research results relate to clinical practice?Can J Psychiatry. 1993 Sep;38 Suppl 3:S75-9. Can J Psychiatry. 1993. PMID: 7504572 Review.
Cited by
-
Guanosine ameliorates positive symptoms of schizophrenia via modulating 5-HT1A and 5-HT2A receptors.Am J Transl Res. 2021 May 15;13(5):4040-4054. eCollection 2021. Am J Transl Res. 2021. PMID: 34149997 Free PMC article.
-
Change of dopamine receptor mRNA expression in lymphocyte of schizophrenic patients.BMC Med Genet. 2001;2:3. doi: 10.1186/1471-2350-2-3. Epub 2001 Mar 5. BMC Med Genet. 2001. PMID: 11252158 Free PMC article.
-
The Canadian experience with risperidone for the treatment of schizophrenia: an overview.J Psychiatry Neurosci. 1998 Sep;23(4):229-39. J Psychiatry Neurosci. 1998. PMID: 9785702 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Medical