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Review
. 1994 Nov;39(9 Suppl 2):S70-5.

Pharmacotherapy of schizophrenia: a review

H K Sigmundson  1
Affiliations
  • PMID: 7533053
Review

Pharmacotherapy of schizophrenia: a review

H K Sigmundson. Can J Psychiatry. 1994 Nov.

Abstract

Traditional antipsychotic medications have targeted the dopamine system. Yet, the isolation and cloning of multiple dopamine receptor subtypes and the recognition of non-dopaminergic pathways (for example, serotonin) in schizophrenia have led to the development of new pharmacological strategies in pharmacotherapy. The author summarizes recent biochemical and pharmacological data and the clinical experience with novel antischizophrenic compounds.

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