[CD5+B cells and autoimmune diseases]
[Article in
Chinese]
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- PMID: 7536147
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[CD5+B cells and autoimmune diseases]
[Article in
Chinese]
Zhonghua Nei Ke Za Zhi.
1994 Sep.
Abstract
By using two colour flow cytometric analysis, we examined the proportion of B lymphocytes bearing CD5 surface antigen (CD5+B cell). The level of CD5+B cells was markedly increased in active chronic ITP and active hyperthyroid patients with Graves' disease. There was an inverse correlation between the percentage of circulating CD5+B cells and platelet counts, and a positive correlation between the level of CD5+B cells in peripheral blood and serum T3 level. These results suggested that the level of CD5+B cells might play a role in producing autoantibodies in some autoimmune diseases.
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