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Review
. 1995 May 12;270(19):11025-8.
doi: 10.1074/jbc.270.19.11025.

Leukocyte trafficking mediated by selectin-carbohydrate interactions

R P McEver  1 , K L Moore, R D Cummings
Affiliations
Free article
Review

Leukocyte trafficking mediated by selectin-carbohydrate interactions

R P McEver et al. J Biol Chem. .
Free article

Abstract

The selectins have attracted intense interest because of their carbohydrate-recognition properties and their pivotal roles in leukocyte trafficking. Future studies will center on the mechanisms for regulating the expression of the selectins and their ligands, the molecular details of selectin binding to glycoprotein ligands and small carbohydrates, and the biophysical principles that selectins employ to mediate attachment and rolling of leukocytes under flow.

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