Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1995 Apr;89(4):927-8.
doi: 10.1111/j.1365-2141.1995.tb08441.x.

Osteoporosis in severe congenital neutropenia treated with granulocyte colony-stimulating factor

N J Bishop  1 , D M Williams, J C Compston, D M Stirling, A Prentice
Affiliations
Case Reports

Osteoporosis in severe congenital neutropenia treated with granulocyte colony-stimulating factor

N J Bishop et al. Br J Haematol. 1995 Apr.

Erratum in

  • Br J Haematol 1995 Jun;90(2):492

Abstract

Recombinant human granulocyte colony-stimulating factor (G-CSF) has substantially improved life expectancy for children with severe congenital neutropenia (SCN). Severe osteoporosis, reported in this population, may relate to the disease process, or be a therapeutic side-effect. This report details bone loss, quantitated absorptiometrically and histomorphometrically, in a child with SCN and vertebral collapse, and the positive response to anabolic steroid and bisphosphonate therapy.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources