Do autoantibodies to IgE play a role in IgE-mediated events?
- PMID: 7541018
- DOI: 10.1038/icb.1995.18
Do autoantibodies to IgE play a role in IgE-mediated events?
Abstract
Elevated blood levels of IgG anti-IgE are detectable in individuals exhibiting enhanced IgE production, namely those with allergic conditions and helminthic parasite infections. The fact that there are epitope-specific subpopulations of autoanti-IgE suggests that this autoantibody could potentially have multiple effects in immunological events involving IgE.