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Review
. 1995 Apr;7(2):228-34.
doi: 10.1016/0952-7915(95)80007-7.

Life and death during lymphocyte development and function: evidence for two distinct killing mechanisms

A Strasser  1
Affiliations
Review

Life and death during lymphocyte development and function: evidence for two distinct killing mechanisms

A Strasser. Curr Opin Immunol. 1995 Apr.

Abstract

During their development and after their functional activation most lymphocytes die, either because they fail to receive a survival signal or because they are actively killed. Recent experiments on Bcl-2 and Fas/Apo-1 have provided evidence that these two death processes are subject to distinct genetic control.

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