Review
doi: 10.1016/0952-7915(95)80112-x.
Mouse NK1+ T cells
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- PMID: 7546402
- DOI: 10.1016/0952-7915(95)80112-x
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Review
Mouse NK1+ T cells
Curr Opin Immunol.
1995 Jun.
Abstract
Mouse NK1+ T cells constitute a special subset of alpha beta TCR+ T cells that express natural killer surface receptors and are thought to play an immunoregulatory role because of their unique ability to secrete IL-4 within minutes of primary activation. The recent discovery that they recognize non-polymorphic MHC class I like ligands encoded by CD1 family genes sheds a new light on unusual aspects of their development as well as on some of the possible ways in which they might influence the regulation of the T-helper cell (types 1 and 2) classes of immune responses.
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