Role of L-threonine dehydrogenase in the catabolism of threonine and synthesis of glycine by Escherichia coli
- PMID: 7548
- PMCID: PMC233149
- DOI: 10.1128/jb.126.3.1245-1249.1976
Role of L-threonine dehydrogenase in the catabolism of threonine and synthesis of glycine by Escherichia coli
Abstract
The enzyme L-threonine dehydrogenase was demonstrated in extracts of Escherichia coli K-12, and was shown to be the first enzyme of the pathway converting threonine to glycine. The enzyme was induced by L-leucine, but not by its substrate, L-threonine. The metabolic significance of leucine as a catabolic signal for amino acid degradation is considered.
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