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. 1995 Apr 24;677(2):341-4.
doi: 10.1016/0006-8993(95)00214-b.

Colocalization of fructose-1,6-bisphosphatase and glial fibrillary acidic protein in rat brain

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Colocalization of fructose-1,6-bisphosphatase and glial fibrillary acidic protein in rat brain

D Schmoll et al. Brain Res. .

Abstract

Immunofluorescence studies of rat brain sections demonstrated an exclusive colocalization of the gluconeogenic key enzyme fructose-1,6-bisphosphatase (FBPase) with the astroglial marker glial fibrillary acidic protein, indicating FBPase in brain as an astrocyte-specific enzyme. This conclusion was supported by the presence of FBPase activity in astroglia-rich but not neuron-rich primary cultures derived from rat brain.

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