Colocalization of fructose-1,6-bisphosphatase and glial fibrillary acidic protein in rat brain
- PMID: 7552262
- DOI: 10.1016/0006-8993(95)00214-b
Colocalization of fructose-1,6-bisphosphatase and glial fibrillary acidic protein in rat brain
Abstract
Immunofluorescence studies of rat brain sections demonstrated an exclusive colocalization of the gluconeogenic key enzyme fructose-1,6-bisphosphatase (FBPase) with the astroglial marker glial fibrillary acidic protein, indicating FBPase in brain as an astrocyte-specific enzyme. This conclusion was supported by the presence of FBPase activity in astroglia-rich but not neuron-rich primary cultures derived from rat brain.
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